Introduction
Ensuring the safety and efficacy of topical products is of utmost importance to protect consumer health and well-being. In this context, a study was conducted to evaluate the dermatological safety of Libain Quick Pain Relief Oil, a topical product provided by Essbrains Pharma Pvt Ltd. The study aimed to assess the potential skin irritation caused by the oil when applied to healthy human subjects for a period of 24 hours under complete occlusion. This blog post will delve into the details and findings of the study.
Methodology
The study enrolled a total of 24 healthy human subjects, all of whom completed the evaluation. The subjects were instructed to apply the Libain Quick Pain Relief Oil on their skin, and the oil was kept in place with an occlusive patch for 24 hours. The subjects; skin was assessed at various time points, including 0 hours, 24 hours, 48 hours, and 7 days after the application.
Results
The study measured the mean irritation scores for each tested formulation, including the Libain Quick Pain Relief Oil and a positive control (SLS). The mean irritation scores were evaluated based on the Draize scale for scoring irritation.
The results indicated that the Libain Quick Pain Relief Oil demonstrated no irritation potential throughout the study. The mean irritation scores for the oil were consistently rated as 0.00 at all time points, indicating that it was non-irritant. On the other hand, the positive control (SLS) exhibited irritant effects, as reflected by the increasing mean irritation scores over the evaluation period.
Discussion
Based on the findings of the study, it can be concluded that the Libain Quick Pain Relief Oil is dermatologically safe for topical application. The oil consistently demonstrated a non-irritant classification when evaluated at 0 hours, 24 hours, 48 hours, and 7 days. This classification aligns with the guidelines outlined in reference BIS 4011:1997, which provides a comprehensive framework for evaluating the safety of topical products.
The presence of a positive control (SLS) in the study further validated the reliability of the results. The positive control consistently exhibited irritant effects, confirming the sensitivity of the study design and the accuracy of the evaluation process.
Conclusion
The dermatological safety evaluation of Libain Quick Pain Relief Oil through a 24-hour patch test under complete occlusion on healthy human subjects yielded positive results. The oil showed no skin irritation potential throughout the study, indicating its safety for topical use. These findings provide reassurance to both healthcare professionals and consumers regarding the products safety profile.
It is essential to conduct such rigorous safety assessments to ensure that topical products meet the highest standards of quality and consumer safety. The study conducted on the Libain Quick Pain Relief Oil exemplifies the commitment of Essbrains Pharma Pvt Ltd to provide safe and effective healthcare solutions.
Disclaimer: This blog post is based on the provided data and should not be considered as medical advice. Please consult a healthcare professional or refer to the products, official documentation for specific usage instructions and guidance.e